Hypertensive kidney disease death rate up 48%: 5 notes

Mortality from hypertensive kidney disease in the U.S. has grown by 48%, according to an abstract presented Sept. 5 at the American Heart Association’s 2025 Hypertension Scientific Sessions.

Researchers analyzed CDC data from 1999 to 2023 to assess changes and trends in the number of deaths associated with hypertensive renal disease.

Here are five notes from the abstract:

1. Between 1999 and 2023, the age-adjusted mortality rate for hypertensive kidney disease grew from 3.3 per 100,000 people to 4.91 per 100,000.

   During the study period, 274,667 deaths were attributed to hypertensive kidney disease in individuals aged 15 and older.

2. Men had a 4.48 average age-adjusted mortality rate, compared to 3.69 for women.
3. Black individuals had the highest average age-adjusted mortality rate at 10.37 per 100,000 people, compared to between 3.33 and 3.90 per 100,000 seen in other populations.
4. Washington, D.C., Tennessee and Mississippi had the highest age-adjusted mortality rates at 7.6, 5.9 and 5.83 per 100,000 people, respectively, while the western U.S. was the region with the highest overall age-adjusted mortality rate at 4.59 per 100,000.
5. “High blood pressure isn’t just about strokes or heart attacks – it’s also a major cause of kidney disease and death, especially in Black and Hispanic communities,” Joiven Nyongbella, MD, from Detroit-based Wayne State University Henry Ford Rochester Hospital, said in the release. “Despite national efforts to reduce health inequalities, Black individuals still had over three times the death rate compared to other groups of people.”

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